Scientific Summaries
At Go North Medical, evidence is the cornerstone of our mission to target the right patients at the right time. In the area of Neurology alone, over 100 articles, case studies, and other resources are published each week. To deepen the company's understanding of the field, the medical team, led by Medical Affairs Manager Martina Boström, extracts key insights from these publications. All medical team members have a research background and possess expertise in critically reviewing evidence to determine both its strengths and weaknesses.
Primarily, the team stays up-to-date with the latest scientific evidence on vagus nerve stimulation therapy and evaluates its effectiveness through critical review and analysis of relevant publications. Part of this effort is published here, with scientific summaries and reflections created by the team. These summaries emphasize the most important publications that are relevant to our field of expertise.
Please don’t hesitate to contact us if you are unable to find clinical evidence related to a particular area of interest.
Efficacy and potential predictors of vagus nerve stimulation therapy in refractory postencephalitic epilepsy
Liu S, Xiong Z, Wang J, Tang C, Deng J, Zhang J, Guo M, Guan Y, Zhou J, Zhai F, Luan G, Li T.
Ther Adv Chronic Dis 2022, Vol. 13: 1–13
Predictors of vagus nerve stimulation complications among pediatric patients with drug-resistant epilepsy
Muthiah N, Sharma N, Vodovotz L, White GE, Abel TJ.
J Neurosurg Pediatr. 2022 Jul 8:1-8.
Preoperative Heart Rate Variability During Sleep Predicts Vagus Nerve Stimulation Outcome Better in Patients With Drug-Resistant Epilepsy
Fang X, Liu HY, Wang ZY, Yang Z, Cheng TY, Hu CH, Hao HW, Meng FG, Guan YG, Ma YS, Liang SL, Lin JL, Zhao MM, Li LM.
Front Neurol. 2021 Jul 7;12:691328.
Prediction of Vagal Nerve Stimulation Efficacy in Drug-Resistant Epilepsy (PRECISE): Prospective Study for Pre-implantation Prediction/Study Design
Have a look at the study design of the upcoming PRediction of vagal nerve stimulation EfficaCy In drug-reSistant Epilepsy (PRECISE) study, by Dolezalova et al. 2022, that was recently published in frontiers in Neurology.
Subgroup analysis of seizure and cognitive outcome after vagal nerve stimulator implantation in children
Knorr C, Greuter L, Constantini S, Fried I, Kremer U, Datta AN, Guzman R, Soleman J.
Child's Nervous System volume 37, pages243–252 (2021)
Connectomic profiling and Vagus nerve stimulation Outcomes Study (CONNECTiVOS): a prospective observational protocol to identify biomarkers of seizure response in children and youth
Siegel L, Yan H, Warsi N, Wong S, Suresh H, Weil AG, Ragheb J, Wang S, Rozzelle C, Albert GW, Raskin J, Abel T, Hauptman J, Schrader DV, Bollo R, Smyth MD, Lew SM, Lopresti M, Kizek DJ, Weiner HL, Fallah A, Widjaja E, Ibrahim GM.
BMJ Open 2022;12:e055886.
Brainstem Associated Somatosensory Evoked Potentials and Response to Vagus Nerve Stimulation: An Investigation of the Vagus Afferent Network
Suresh H, Mithani K, Brar K, Yan H, Strantzas S, Vandenberk M, Sharma R, Yau I, Go C, Pang E, Kerr E, Ochi A, Otsubo H, Jain P, Donner E, Snead OC, Ibrahim GM. #RetrospectiveStudy
Front. Neurol., 18 February 2022