Scientific Summaries
At Go North Medical, evidence is the cornerstone of our mission to target the right patients at the right time. In the area of Neurology alone, over 100 articles, case studies, and other resources are published each week. To deepen the company's understanding of the field, the medical team, led by Medical Affairs Manager Martina Boström, extracts key insights from these publications. All medical team members have a research background and possess expertise in critically reviewing evidence to determine both its strengths and weaknesses.
Primarily, the team stays up-to-date with the latest scientific evidence on vagus nerve stimulation therapy and evaluates its effectiveness through critical review and analysis of relevant publications. Part of this effort is published here, with scientific summaries and reflections created by the team. These summaries emphasize the most important publications that are relevant to our field of expertise.
Please don’t hesitate to contact us if you are unable to find clinical evidence related to a particular area of interest.
Vagus nerve stimulation reduces cardiac electrical instability assessed by quantitative T-wave alternans analysis in patients with drug-resistant focal epilepsy
Schomer AC, Nearing BD, Schachter SC, Verrier RL.
Epilepsia. 2014 Dec;55(12):1996-2002.
Long-term follow-up of vagus nerve stimulation in drug-resistant KCNT1-related epilepsy: a case presentation
Wang, M., Geng, G., Meng, Y. et al.
Acta Epileptologica 4, 34 (2022).
Scheduled Programming of VNS Therapy Reduces Time-To-Dose and Office Visits in the COVID-19 Pandemic (P5-1.006)
Maxine Dibue, Roshani Patel, Michal Tzadok, Firas Fahoum, Charles Gordon, Riem El Tahry
Neurology Apr 2023, 100 (17 Supplement 2) 3974;
Vagus Nerve Stimulation for Refractory Epilepsy in Tuberous Sclerosis
Zamponi N, Petrelli C, Passamonti C, Moavero R, Curatolo P.
Pediatr Neurol. 2010 Jul;43(1):29-34.
Impact of Vagus Nerve Stimulation for the Treatment of Drug-Resistant Epilepsy on Patterns of Use and Cost of Health Care Services and Pharmacotherapy [...]
Evans K, Stamas N, Li Q, Vincent T, Halchenko Y, Zhang L, Danielson V, Murphy J, Barion F, Lam S, Lassagne R, Berger A.
Clin Ther. 2023 Feb 4:S0149-2918(23)00027-9.
Refractory epilepsy in tuberous sclerosis: Vagus nerve stimulation with or without subsequent resective surgery
Wang, M., Geng, G., Meng, Y. et al.
Acta Epileptologica 4, 34 (2022).
Vagus nerve stimulation for intractable epilepsy in tuberous sclerosis complex
Major P, Thiele EA.
Epilepsy Behav. 2008 Aug;13(2):357-60.
Clinical Benefit of Vagus Nerve Stimulation for Epilepsy: Assessment of Randomized Controlled Trials and Prospective Non-Randomized Studies
Cramer SW, McGovern RA, Chen CC, Park MC.
J Cent Nerv Syst Dis. 2023 Jan 11;15:11795735231151830.
How patients' psycho-social profiles contribute to decision-making in epilepsy surgery: A prospective study
Hohmann L, Bien CG, Holtkamp M, Grewe P.
Epilepsia. 2023 Mar;64(3):678-691.
Long-term outcomes and prognosis factors of vagus nerve stimulation in patients with refractory epilepsy
Cuiping X, Hua L, Jiwen X, Xiaohua Z, Guiliang H, Qiang Qiang L, Chengyun D, Shan W, Quanjun Z, Xiaojun B, Kui C, Duanyu N, Yongjie L, Tao Y, Yuping W.
Acta Epileptologica 4, 38 (2022).
Clinical course of young patients with Dravet syndrome after vagal nerve stimulation
Zamponi N, Passamonti C, Cappanera S, Petrelli C.
Eur J Paediatr Neurol. 2011 Jan;15(1):8-14.
Surgical Treatment of Drug-Resistant Generalized Epilepsy
Bullinger KL, Alwaki A, Gross RE.
Curr Neurol Neurosci Rep. 2022 Aug;22(8):459-465.
Alteration in brain connectivity in patients with Dravet syndrome after vagus nerve stimulation (VNS): exploration of its effectiveness using graph theory analysis with electroencephalography
Wang ZJ, Kim ES, Noh BH, Liang JG, Lee D, Hur YJ, Kim NY, Kim HD.
J Neural Eng. 2020 Jun 22;17(3):036014.
Early surgical approaches in pediatric epilepsy — a systematic review and meta-analysis
Frank NA, Greuter L, Guzman R, Soleman J.
Childs Nerv Syst. 2023 Mar;39(3):677-688.
Efficacy of adjunctive vagus nerve stimulation in patients with Dravet syndrome: A meta-analysis of 68 patients
Dibué-Adjei M, Fischer I, Steiger HJ, Kamp MA.
Seizure. 2017 Aug;50:147-152.
Emerging Trends in Neuromodulation for Treatment of Drug-Resistant Epilepsy
Abouelleil M, Deshpande N, Ali R.
Front Pain Res (Lausanne). 2022 Mar 21;3:839463.
Efficacy and potential predictors of vagus nerve stimulation therapy in refractory postencephalitic epilepsy
Liu S, Xiong Z, Wang J, Tang C, Deng J, Zhang J, Guo M, Guan Y, Zhou J, Zhai F, Luan G, Li T.
Ther Adv Chronic Dis 2022, Vol. 13: 1–13
Neuromodulation in drug-resistant epilepsy: A review of current knowledge
Xue T, Chen S, Bai Y, Han C, Yang A, Zhang J.
Acta Neurol Scand. 2022 Sep 5.
Patient-Specific Characteristics Associated with Favorable Response to Vagus Nerve Stimulation
Riestenberg RA, Sherman AE, Clark AJS, Shahlaie K, Zwienenberg M, Alden T, Bandt SK
World Neurosurg. 2022 May;161:e608-e624.
Vagus nerve stimulation in patients with therapy-resistant generalized epilepsy
Suller Marti A, Mirsattari SM, MacDougall K, Steven DA, Parrent A, de Ribaupierre S, Andrade A, Diosy D, McLachlan RS, Burneo JG.
Epilepsy Behav. 2020 Oct;111:107253.