Concurrent brain-responsive and vagus nerve stimulation for treatment of drug-resistant focal epilepsy

Adult
Written By Rodrigo Silva

Brown MG, Sillau S, McDermott D, Ernst LD, Spencer DC, Englot DJ, González HFJ, Datta P, Karakis I, Becker D, Rolston JD, Arain A, Rao VR, Doherty M, Urban A, Drees C.
Epilepsy & Behavior Volume 129, April 2022, 108653
http://ow.ly/vwHO50Iq3K7

Hot Off The Press - This new #retrospective chart review by Brown et al. 2022 examined the efficacy and safety of concomitant vagus nerve stimulation (#VNS) and responsive neurostimulation (#RNS) for the treatment of drug-resistant focal epilepsy in adult patients.

The study found that 98% of the patients (N=64) underwent RNS implantation after VNS insertion. The addition of RNS to VNS improved seizure frequency reduction, both at the one-year follow-up and at the last follow-up (median duration: 28 months). Furthermore, dual neuromodulation was well-tolerated with no negative interactions.

 
 
Rodrigo Silva
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Brainstem Associated Somatosensory Evoked Potentials and Response to Vagus Nerve Stimulation: An Investigation of the Vagus Afferent Network
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Norwegian population-based study of long-term effects, safety, and predictors of response of vagus nerve stimulation treatment in drug-resistant epilepsy: The NORPulse study.