Potential roles of vagus nerve stimulation on traumatic brain injury: Evidence from in vivo and clinical studies

AdultPediatric

Jan 31

Srihagulang C, Vongsfak J, Vaniyapong T, Chattipakorn N, Chattipakorn SC.

Exp Neurol. 2022 Jan;347:113887.
https://doi.org/10.1016/j.expneurol.2021.113887

Traumatic brain injury (#TBI) is a brain injury caused by an external force. Even though there are massive studies about its pathophysiology, effective treatments for TBI are still lacking. This new review by Srihagulang et al. (Jan. 2022) summarized the preclinical and clinical evidence for the beneficial effects of vagus nerve stimulation (#VNS) on TBI and discussed the possible mechanisms, including its effects of neurotransmitter regulation, anti-inflammation, attenuation the breakdown of the blood-brain barrier and brain edema, and noradrenergic mechanism.

VagusNerveStimulationTraumaticBrainInjuryMechanismBrainInjury

Rodrigo Silva

Potential roles of vagus nerve stimulation on traumatic brain injury: Evidence from in vivo and clinical studies

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