Scientific Summaries
At Go North Medical, evidence is the cornerstone of our mission to target the right patients at the right time. In the area of Neurology alone, over 100 articles, case studies, and other resources are published each week. To deepen the company's understanding of the field, the medical team, led by Medical Affairs Manager Martina Boström, extracts key insights from these publications. All medical team members have a research background and possess expertise in critically reviewing evidence to determine both its strengths and weaknesses.
Primarily, the team stays up-to-date with the latest scientific evidence on vagus nerve stimulation therapy and evaluates its effectiveness through critical review and analysis of relevant publications. Part of this effort is published here, with scientific summaries and reflections created by the team. These summaries emphasize the most important publications that are relevant to our field of expertise.
Please don’t hesitate to contact us if you are unable to find clinical evidence related to a particular area of interest.
Long-term follow-up of vagus nerve stimulation in drug-resistant KCNT1-related epilepsy: a case presentation
Wang, M., Geng, G., Meng, Y. et al.
Acta Epileptologica 4, 34 (2022).
Scheduled Programming of VNS Therapy Reduces Time-To-Dose and Office Visits in the COVID-19 Pandemic (P5-1.006)
Maxine Dibue, Roshani Patel, Michal Tzadok, Firas Fahoum, Charles Gordon, Riem El Tahry
Neurology Apr 2023, 100 (17 Supplement 2) 3974;
The role of vagus nerve stimulation in genetic etiologies of drug-resistant epilepsy: a meta-analysis
Hajtovic S, LoPresti MA, Zhang L, Katlowitz KA, Kizek DJ, Lam S.
J Neurosurg Pediatr. 2022 Mar 18:1-14.
Vagus nerve stimulation for treatment of epilepsy in Rett syndrome
Dev Med Child Neurol. 2006 Aug;48(8):683-6.
doi: 10.1017/S0012162206001435. PMID: 16836782.
Vagus nerve stimulation for drug-resistant epilepsy induced by tuberous sclerosis complex
Tong X, Wang X, Qin L, Zhou J, Guan Y, Teng P, Wang J, Yang Y, Li T, Luan G.
Epilepsy Behav. 2022 Jan;126:108431.
Vagus Nerve Stimulation for Refractory Epilepsy in Tuberous Sclerosis
Zamponi N, Petrelli C, Passamonti C, Moavero R, Curatolo P.
Pediatr Neurol. 2010 Jul;43(1):29-34.
Impact of Vagus Nerve Stimulation for the Treatment of Drug-Resistant Epilepsy on Patterns of Use and Cost of Health Care Services and Pharmacotherapy [...]
Evans K, Stamas N, Li Q, Vincent T, Halchenko Y, Zhang L, Danielson V, Murphy J, Barion F, Lam S, Lassagne R, Berger A.
Clin Ther. 2023 Feb 4:S0149-2918(23)00027-9.
Refractory epilepsy in tuberous sclerosis: Vagus nerve stimulation with or without subsequent resective surgery
Wang, M., Geng, G., Meng, Y. et al.
Acta Epileptologica 4, 34 (2022).
Vagus nerve stimulation for intractable epilepsy in tuberous sclerosis complex
Major P, Thiele EA.
Epilepsy Behav. 2008 Aug;13(2):357-60.
Clinical Benefit of Vagus Nerve Stimulation for Epilepsy: Assessment of Randomized Controlled Trials and Prospective Non-Randomized Studies
Cramer SW, McGovern RA, Chen CC, Park MC.
J Cent Nerv Syst Dis. 2023 Jan 11;15:11795735231151830.
The role of vagus nerve stimulation in genetic etiologies of drug-resistant epilepsy: a meta-analysis.
Many caregivers are concerned about the potential long-term effects of using antiseizure medications (#ASMs) and how it may affect their children’s intelligence.
Long-term outcomes and prognosis factors of vagus nerve stimulation in patients with refractory epilepsy
Cuiping X, Hua L, Jiwen X, Xiaohua Z, Guiliang H, Qiang Qiang L, Chengyun D, Shan W, Quanjun Z, Xiaojun B, Kui C, Duanyu N, Yongjie L, Tao Y, Yuping W.
Acta Epileptologica 4, 38 (2022).
Clinical course of young patients with Dravet syndrome after vagal nerve stimulation
Zamponi N, Passamonti C, Cappanera S, Petrelli C.
Eur J Paediatr Neurol. 2011 Jan;15(1):8-14.
Surgical Treatment of Drug-Resistant Generalized Epilepsy
Bullinger KL, Alwaki A, Gross RE.
Curr Neurol Neurosci Rep. 2022 Aug;22(8):459-465.
Early surgical approaches in pediatric epilepsy — a systematic review and meta-analysis
Frank NA, Greuter L, Guzman R, Soleman J.
Childs Nerv Syst. 2023 Mar;39(3):677-688.
Efficacy of adjunctive vagus nerve stimulation in patients with Dravet syndrome: A meta-analysis of 68 patients
Dibué-Adjei M, Fischer I, Steiger HJ, Kamp MA.
Seizure. 2017 Aug;50:147-152.
Emerging Trends in Neuromodulation for Treatment of Drug-Resistant Epilepsy
Abouelleil M, Deshpande N, Ali R.
Front Pain Res (Lausanne). 2022 Mar 21;3:839463.
Vagus nerve stimulation in children with drug-resistant epilepsy of monogenic etiology
Xie H, Ma J, Ji T, Liu Q, Cai L, Wu Y.
Front Neurol. 2022 Sep 1;13:951850.
Efficacy and potential predictors of vagus nerve stimulation therapy in refractory postencephalitic epilepsy
Liu S, Xiong Z, Wang J, Tang C, Deng J, Zhang J, Guo M, Guan Y, Zhou J, Zhai F, Luan G, Li T.
Ther Adv Chronic Dis 2022, Vol. 13: 1–13
Evaluating vagus nerve stimulation treatment with heart rate monitoring in pediatric patients with intractable epilepsy
Brandon Santhumayor, Shefali Karkare, Sanjeev Kothare & Shaun Rodgers
Epileptic Disord. 2022 Oct 1;24(5):1-12.