Scientific Summaries
At Go North Medical, evidence is the cornerstone of our mission to target the right patients at the right time. In the area of Neurology alone, over 100 articles, case studies, and other resources are published each week. To deepen the company's understanding of the field, the medical team, led by Medical Affairs Manager Martina Boström, extracts key insights from these publications. All medical team members have a research background and possess expertise in critically reviewing evidence to determine both its strengths and weaknesses.
Primarily, the team stays up-to-date with the latest scientific evidence on vagus nerve stimulation therapy and evaluates its effectiveness through critical review and analysis of relevant publications. Part of this effort is published here, with scientific summaries and reflections created by the team. These summaries emphasize the most important publications that are relevant to our field of expertise.
Please don’t hesitate to contact us if you are unable to find clinical evidence related to a particular area of interest.
Alteration in brain connectivity in patients with Dravet syndrome after vagus nerve stimulation (VNS): exploration of its effectiveness using graph theory analysis with electroencephalography
Wang ZJ, Kim ES, Noh BH, Liang JG, Lee D, Hur YJ, Kim NY, Kim HD.
J Neural Eng. 2020 Jun 22;17(3):036014.
A prediction model integrating synchronization biomarkers and clinical features to identify responders to vagus nerve stimulation among pediatric patients with drug-resistant epilepsy
Ma J, Wang Z, Cheng T, Hu Y, Qin X, Wang W, Yu G, Liu Q, Ji T, Xie H, Zha D, Wang S, Yang Z, Liu X, Cai L, Jiang Y, Hao H, Wang J, Li L, Wu Y.
CNS Neurosci Ther. 2022 Jul 27
Automated detection of nocturnal motor seizures using an audio-video system
Armand Larsen S, Terney D, Østerkjerhuus T, Vinding Merinder T, Annala K, Knight A, Beniczky S.
Brain Behav. 2022 Aug 8:e2737
Accurate identification of EEG recordings with interictal epileptiform discharges using a hybrid approach: Artificial intelligence supervised by human experts
Kural MA, Jing J, Fürbass F, Perko H, Qerama E, Johnsen B, Fuchs S, Westover MB, Beniczky S.
Epilepsia. 2022;00:1–10.
Prediction of Vagal Nerve Stimulation Efficacy in Drug-Resistant Epilepsy (PRECISE): Prospective Study for Pre-implantation Prediction/Study Design
Have a look at the study design of the upcoming PRediction of vagal nerve stimulation EfficaCy In drug-reSistant Epilepsy (PRECISE) study, by Dolezalova et al. 2022, that was recently published in frontiers in Neurology.
Semiautomated classification of nocturnal seizures using video recordings
Peltola J, Basnyat P, Armand Larsen S, Østerkjaerhuus T, Vinding Merinder T, Terney D, Beniczky S.
Epilepsia. 2022;00:1–7.
Automated detection of absence seizures using a wearable electroencephalographic device: a phase 3 validation study and feasibility of automated behavioral testing.
Japaridze G, Loeckx D, Buckinx T, Armand Larsen S, Proost R, Jansen K, MacMullin P, Paiva N, Kasradze S, Rotenberg A, Lagae L, Beniczky S.
Epilepsia. 2022;00:1–7.
Reasons for not having epilepsy surgery
Khoo A, de Tisi J, Mannan S, O'Keeffe AG, Sander JW, Duncan JS.
Epilepsia. 2021 Dec;62(12):2909-2919.
Electrocorticography Analysis in Patients With Dual Neurostimulators Supports Desynchronization as a Mechanism of Action for Acute Vagal Nerve Stimulator Stimulation
Lia D Ernst, Paul J Steffan, Priya Srikanth, Jack Wiedrick, David C Spencer, Proleta Datta, Navya M Joseph, Magda Wernovsky, Danielle A Becker
J Clin Neurophysiol. 2021 Apr 7.