Scientific Summaries
At Go North Medical, evidence is the cornerstone of our mission to target the right patients at the right time. In the area of Neurology alone, over 100 articles, case studies, and other resources are published each week. To deepen the company's understanding of the field, the medical team, led by Medical Affairs Manager Martina Boström, extracts key insights from these publications. All medical team members have a research background and possess expertise in critically reviewing evidence to determine both its strengths and weaknesses.
Primarily, the team stays up-to-date with the latest scientific evidence on vagus nerve stimulation therapy and evaluates its effectiveness through critical review and analysis of relevant publications. Part of this effort is published here, with scientific summaries and reflections created by the team. These summaries emphasize the most important publications that are relevant to our field of expertise.
Please don’t hesitate to contact us if you are unable to find clinical evidence related to a particular area of interest.
Surgical Treatment of Drug-Resistant Generalized Epilepsy
Bullinger KL, Alwaki A, Gross RE.
Curr Neurol Neurosci Rep. 2022 Aug;22(8):459-465.
Patient-Specific Characteristics Associated with Favorable Response to Vagus Nerve Stimulation
Riestenberg RA, Sherman AE, Clark AJS, Shahlaie K, Zwienenberg M, Alden T, Bandt SK
World Neurosurg. 2022 May;161:e608-e624.
Practical considerations in epilepsy neurostimulation
Simpson HD, Schulze-Bonhage A, Cascino GD, Fisher RS, Jobst BC, Sperling MR, Lundstrom BN
Epilepsia. 2022 Oct;63(10):2445-2460.
Vagus nerve stimulation outcome prediction: from simple parameters to advanced models
Chrastina J, Novak Z, Zeman T, Dolezalova I, Zatloukalova E, Brazdil M.
Bratisl Lek Listy. 2022;123(9):641-647.
A prediction model integrating synchronization biomarkers and clinical features to identify responders to vagus nerve stimulation among pediatric patients with drug-resistant epilepsy
Ma J, Wang Z, Cheng T, Hu Y, Qin X, Wang W, Yu G, Liu Q, Ji T, Xie H, Zha D, Wang S, Yang Z, Liu X, Cai L, Jiang Y, Hao H, Wang J, Li L, Wu Y.
CNS Neurosci Ther. 2022 Jul 27
Preoperative Heart Rate Variability During Sleep Predicts Vagus Nerve Stimulation Outcome Better in Patients With Drug-Resistant Epilepsy
Fang X, Liu HY, Wang ZY, Yang Z, Cheng TY, Hu CH, Hao HW, Meng FG, Guan YG, Ma YS, Liang SL, Lin JL, Zhao MM, Li LM.
Front Neurol. 2021 Jul 7;12:691328.
Norwegian population-based study of long-term effects, safety, and predictors of response of vagus nerve stimulation treatment in drug-resistant epilepsy: The NORPulse study.
Many caregivers are concerned about the potential long-term effects of using antiseizure medications (#ASMs) and how it may affect their children’s intelligence.