Epilepsy surgery in the first six months of life: A systematic review and meta-analysis

Makridis KL, Atalay DA, Thomale UW, Tietze A, Elger CE, Kaindl AM.
Seizure: European Journal of Epilepsy 96 (2022) 109–117
https://doi.org/10.1016/j.seizure.2022.02.009

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Have a look at this new #review and metaanalysis by Makridis et al. 2022 examining the safety and outcome parameters of epilepsy surgery in infants (≤6 months old) with drug resistant epilepsy (#DRE).

The systematic literature search identified 16 publications and 158 cases to be included in the metaanalysis. The results indicated exceptional #seizure control, with 89% of the patients experiencing a reduction in seizure burden, post surgery. Noteworthy, two out of three patients became seizure free post intervention. For these patients, beneficial effects on #cognition was more common.