Scientific Summaries

At Go North Medical, evidence is the cornerstone of our mission to target the right patients at the right time. In the area of Neurology alone, over 100 articles, case studies, and other resources are published each week. To deepen the company's understanding of the field, the medical team, led by Medical Affairs Manager Martina Boström, extracts key insights from these publications. All medical team members have a research background and possess expertise in critically reviewing evidence to determine both its strengths and weaknesses.

Primarily, the team stays up-to-date with the latest scientific evidence on vagus nerve stimulation therapy and evaluates its effectiveness through critical review and analysis of relevant publications. Part of this effort is published here, with scientific summaries and reflections created by the team. These summaries emphasize the most important publications that are relevant to our field of expertise.

Please don’t hesitate to contact us if you are unable to find clinical evidence related to a particular area of interest.

Rodrigo Silva 10/1/22 Rodrigo Silva 10/1/22

Cumulative effects of antiseizure medication on intelligence in children with focal epilepsy

Stevering CH, Lamberink HJ, Woodfield J, van Schooneveld M, Otte WM, Chin RFM, Bastin ME, Geleijns K, Braun KPJ.

Epileptic Disord. 2022 Oct 1;24(5):1-12. English.

Rodrigo Silva 8/31/22 Rodrigo Silva 8/31/22

A prediction model integrating synchronization biomarkers and clinical features to identify responders to vagus nerve stimulation among pediatric patients with drug-resistant epilepsy

Ma J, Wang Z, Cheng T, Hu Y, Qin X, Wang W, Yu G, Liu Q, Ji T, Xie H, Zha D, Wang S, Yang Z, Liu X, Cai L, Jiang Y, Hao H, Wang J, Li L, Wu Y.

CNS Neurosci Ther. 2022 Jul 27

Rodrigo Silva 8/8/22 Rodrigo Silva 8/8/22

Predictors of vagus nerve stimulation complications among pediatric patients with drug-resistant epilepsy

Muthiah N, Sharma N, Vodovotz L, White GE, Abel TJ.

J Neurosurg Pediatr. 2022 Jul 8:1-8.

Rodrigo Silva 8/3/22 Rodrigo Silva 8/3/22

Comparison of traditional and closed loop vagus nerve stimulation for treatment of pediatric drug-resistant epilepsy: A propensity-matched retrospective cohort study

Muthiah N, Akwayena E, Vodovotz L, Sharma N, Jeong JH, White GE, Abel TJ.

Seizure. 2022 Jan;94:74-81.

Rodrigo Silva 6/14/22 Rodrigo Silva 6/14/22

Clinician preferences for neurotechnologies in pediatric drug- resistant epilepsy: A discrete choice experiment

Glory O. Apantaku, Patrick J. McDonald, Magda Aguiar, Laura Y. Cabrera, Winston Chiong, Mary B. Connolly, Viorica Hrincu, George M. Ibrahim, K. Julia Kaal, Ashley Lawson, Robert Naftel, Eric Racine, Abdollah Safari, Mark Harrison, Judy Illes

Epilepsia. 2022;00:1–12

Rodrigo Silva 5/31/22 Rodrigo Silva 5/31/22

Epilepsy surgery in the first six months of life: A systematic review and meta-analysis

Makridis KL, Atalay DA, Thomale UW, Tietze A, Elger CE, Kaindl AM.

Seizure: European Journal of Epilepsy 96 (2022) 109–117

Rodrigo Silva 5/25/22 Rodrigo Silva 5/25/22

Vagal nerve stimulation for drug-resistant epilepsies in different age, aetiology and duration

Colicchio G, Policicchio D, Barbati G, Cesaroni E, Fuggetta F, Meglio M, Papacci F, Rychlicki F, Scerrati M, Zamponi N.

Child's Nervous System volume 26, pages811–819 (2010)

Rodrigo Silva 5/19/22 Rodrigo Silva 5/19/22

Subgroup analysis of seizure and cognitive outcome after vagal nerve stimulator implantation in children

Knorr C, Greuter L, Constantini S, Fried I, Kremer U, Datta AN, Guzman R, Soleman J.

Child's Nervous System volume 37, pages243–252 (2021)

Rodrigo Silva 5/2/22 Rodrigo Silva 5/2/22

A surface electrode adjacent to vagal nerve stimulator lead can aid in characterizing vagal nerve stimulator mediated pediatric sleep-disordered breathing: a case series of 7 patients

A potential side effect associated with vagus nerve stimulation (#VNS) Therapy for drug resistant epilepsy (#DRE) is sleep-disordered breathing (#SDB).