Vagus nerve stimulation for difficult to treat depression

AdultPediatric
Written By Rodrigo Silva

C. Reif-Leonhard, A. Reif, B. T. Baune & E. Kavakbasi

Nervenarzt. 2022 Apr 5.
doi: 10.1007/s00115-022-01282-6.

This #review by Reif-Leonhard et al. (Apr. 2022) discussed the scientific and clinical evidence for vagus nerve stimulation (#VNS) as an adjunct treatment for treatment-resistant depression (#TRD). Patient selection, perioperative management, follow-up including dosing, and a comparison of international #guidelines for VNS were discussed. 

Results showed that VNS is an approved, effective, and long-term therapy for TRD. More evidence for the sham-controlled studies with long-term follow-up was needed.


Rodrigo Silva
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Difficult-to-Treat Depression and the Role of Vagus Nerve Stimulation