Vagus nerve stimulation: An update on a novel treatment for treatment-resistant depression
Kamel LY, Xiong W, Gott BM, Kumar A, Conway CR.
J Neurol Sci. 2022 Mar 15;434:120171.
https://doi.org/10.1016/j.jns.2022.120171
Hot of the press - This new #review by Kamel et al. provides an updated overview of vagus nerve stimulation (#VNS) therapy in treatment-resistant #depression (#TRD). The review covers #antidepressant effect of VNS therapy, neuroanatomy of the vagus nerve and proposed mechanism of action (#MOA).
Published evidence over the last two decades show that the antidepressant beneficial effects occur over several months and are long-lasting. Further, the studies also support that VNS therapy can improve quality of life (#QOL) and may lower #suicidality.