Scientific Summaries
At Go North Medical, evidence is the cornerstone of our mission to target the right patients at the right time. In the area of Neurology alone, over 100 articles, case studies, and other resources are published each week. To deepen the company's understanding of the field, the medical team, led by Medical Affairs Manager Martina Boström, extracts key insights from these publications. All medical team members have a research background and possess expertise in critically reviewing evidence to determine both its strengths and weaknesses.
Primarily, the team stays up-to-date with the latest scientific evidence on vagus nerve stimulation therapy and evaluates its effectiveness through critical review and analysis of relevant publications. Part of this effort is published here, with scientific summaries and reflections created by the team. These summaries emphasize the most important publications that are relevant to our field of expertise.
Please don’t hesitate to contact us if you are unable to find clinical evidence related to a particular area of interest.
Automated detection of absence seizures using a wearable electroencephalographic device: a phase 3 validation study and feasibility of automated behavioral testing.
Japaridze G, Loeckx D, Buckinx T, Armand Larsen S, Proost R, Jansen K, MacMullin P, Paiva N, Kasradze S, Rotenberg A, Lagae L, Beniczky S.
Epilepsia. 2022;00:1–7.
Dual-Device Neuromodulation in Epilepsy
Freund B, Grewal SS, Middlebrooks EH, Moniz-Garcia D, Feyissa AM, Tatum WO.
World Neurosurg. 2022 Feb 18;S1878-8750(22)00205-4
Combined use of the ketogenic diet and vagus nerve stimulation in pediatric drug‐resistant epilepsy
Wang, M., Geng, G., Meng, Y. et al.
Acta Epileptologica 4, 34 (2022).
Combined ketogenic diet and vagus nerve stimulation: rational polytherapy?
Kossoff EH, Pyzik PL, Rubenstein JE, Bergqvist AG, Buchhalter JR, Donner EJ, Nordli DR Jr, Wheless JW.
Epilepsia. 2007 Jan;48(1):77-81.
Potential roles of vagus nerve stimulation on traumatic brain injury: Evidence from in vivo and clinical studies
Srihagulang C, Vongsfak J, Vaniyapong T, Chattipakorn N, Chattipakorn SC.
Exp Neurol. 2022 Jan;347:113887.
Reasons for not having epilepsy surgery
Khoo A, de Tisi J, Mannan S, O'Keeffe AG, Sander JW, Duncan JS.
Epilepsia. 2021 Dec;62(12):2909-2919.
Electrocorticography Analysis in Patients With Dual Neurostimulators Supports Desynchronization as a Mechanism of Action for Acute Vagal Nerve Stimulator Stimulation
Lia D Ernst, Paul J Steffan, Priya Srikanth, Jack Wiedrick, David C Spencer, Proleta Datta, Navya M Joseph, Magda Wernovsky, Danielle A Becker
J Clin Neurophysiol. 2021 Apr 7.
Closed-loop vagal nerve stimulation for intractable epilepsy: A single-center experience
Graham M. Winston, Sergio Guadix, Miguel Tusa Lavieri, Rafael Uribe-Cardenas, Gary Kocharian, Nicholas Williams, Evan Sholle, Zachary Grinspan, Caitlin E. Hoffman
Seizure. 2021 May;88:95-101.
Long-term surveillance of SUDEP in drug-resistant epilepsypatients treated with VNS therapy
Ryvlin P, So EL, Gordon CM, Hesdorffer DC, Sperling MR, Devinsky O, Bunker MT, Olin B, Friedman D.
Epilepsia. 2018 Mar;59(3):562-572.