Scientific Summaries
At Go North Medical, evidence is the cornerstone of our mission to target the right patients at the right time. In the area of Neurology alone, over 100 articles, case studies, and other resources are published each week. To deepen the company's understanding of the field, the medical team, led by Medical Affairs Manager Martina Boström, extracts key insights from these publications. All medical team members have a research background and possess expertise in critically reviewing evidence to determine both its strengths and weaknesses.
Primarily, the team stays up-to-date with the latest scientific evidence on vagus nerve stimulation therapy and evaluates its effectiveness through critical review and analysis of relevant publications. Part of this effort is published here, with scientific summaries and reflections created by the team. These summaries emphasize the most important publications that are relevant to our field of expertise.
Please don’t hesitate to contact us if you are unable to find clinical evidence related to a particular area of interest.
Brainstem Associated Somatosensory Evoked Potentials and Response to Vagus Nerve Stimulation: An Investigation of the Vagus Afferent Network
Suresh H, Mithani K, Brar K, Yan H, Strantzas S, Vandenberk M, Sharma R, Yau I, Go C, Pang E, Kerr E, Ochi A, Otsubo H, Jain P, Donner E, Snead OC, Ibrahim GM. #RetrospectiveStudy
Front. Neurol., 18 February 2022
Concurrent brain-responsive and vagus nerve stimulation for treatment of drug-resistant focal epilepsy
Brown MG, Sillau S, McDermott D, Ernst LD, Spencer DC, Englot DJ, González HFJ, Datta P, Karakis I, Becker D, Rolston JD, Arain A, Rao VR, Doherty M, Urban A, Drees C.
Epilepsy & Behavior Volume 129, April 2022, 108653
Semiautomated classification of nocturnal seizures using video recordings
Peltola J, Basnyat P, Armand Larsen S, Østerkjaerhuus T, Vinding Merinder T, Terney D, Beniczky S.
Epilepsia. 2022;00:1–7.
Laryngeal Muscle-Evoked Potential Recording as an Indicator of Vagal Nerve Fiber Activation
Bouckaert C, Raedt R, Larsen LE, El Tahry R, Gadeyne S, Carrette E, Proesmans S, Dewaele F, Delbeke J, De Herdt V, Meurs A, Mertens A, Boon P, Vonck K.
Neuromodulation. 2022 Feb 14;S1094-7159(22)00035-6.
Neuromodulation in Intractable Epilepsy Through Responsive Vagal Nerve Stimulation: A Three-Year Retrospective Study at the University of Texas Medical Branch, Galveston
Villarreal J, Valaparla VL, Curtis K, Thottempudi N, Elrahi S, Gil Guevara A, Gogia B, Sun R, Masel T, Rai P.
Cureus 13(10): e18698.
Automated detection of absence seizures using a wearable electroencephalographic device: a phase 3 validation study and feasibility of automated behavioral testing.
Japaridze G, Loeckx D, Buckinx T, Armand Larsen S, Proost R, Jansen K, MacMullin P, Paiva N, Kasradze S, Rotenberg A, Lagae L, Beniczky S.
Epilepsia. 2022;00:1–7.
Dual-Device Neuromodulation in Epilepsy
Freund B, Grewal SS, Middlebrooks EH, Moniz-Garcia D, Feyissa AM, Tatum WO.
World Neurosurg. 2022 Feb 18;S1878-8750(22)00205-4
ILAE clinical practice recommendations for the medical treatment of depression in adults with epilepsy.
Mula M, Brodie MJ, de Toffol B, Guekht A, Hecimovic H, Kanemoto K, Kanner AM, Teixeira AL, Wilson SJ.
Epilepsia. 2022 Feb;63(2):316-334.
Prevalence and associated risk factors of undiagnosed depression among people with epilepsy in a multiethnic society
Tan JK, Khoo CS, Beh HC, Hod R, Baharudin A, Yahya WNNW, Tan HJ.
Epilepsy Research Volume 178, December 2021, 106772
Effect of Long-Term Treatment with Vagus Nerve Stimulation on Mood and Quality of Life in Korean Patients with Drug-Resistant Epilepsy.
Kim JS, Kim DY, Jo HJ, Hwang YH, Song JY, Yang KI, Hong SB.
J Clin Neurol 2021;17(3):385-392
Combined ketogenic diet and vagus nerve stimulation: rational polytherapy?
Kossoff EH, Pyzik PL, Rubenstein JE, Bergqvist AG, Buchhalter JR, Donner EJ, Nordli DR Jr, Wheless JW.
Epilepsia. 2007 Jan;48(1):77-81.
Potential roles of vagus nerve stimulation on traumatic brain injury: Evidence from in vivo and clinical studies
Srihagulang C, Vongsfak J, Vaniyapong T, Chattipakorn N, Chattipakorn SC.
Exp Neurol. 2022 Jan;347:113887.
Reasons for not having epilepsy surgery
Khoo A, de Tisi J, Mannan S, O'Keeffe AG, Sander JW, Duncan JS.
Epilepsia. 2021 Dec;62(12):2909-2919.
Electrocorticography Analysis in Patients With Dual Neurostimulators Supports Desynchronization as a Mechanism of Action for Acute Vagal Nerve Stimulator Stimulation
Lia D Ernst, Paul J Steffan, Priya Srikanth, Jack Wiedrick, David C Spencer, Proleta Datta, Navya M Joseph, Magda Wernovsky, Danielle A Becker
J Clin Neurophysiol. 2021 Apr 7.
Closed-loop vagal nerve stimulation for intractable epilepsy: A single-center experience
Graham M. Winston, Sergio Guadix, Miguel Tusa Lavieri, Rafael Uribe-Cardenas, Gary Kocharian, Nicholas Williams, Evan Sholle, Zachary Grinspan, Caitlin E. Hoffman
Seizure. 2021 May;88:95-101.
Long-term surveillance of SUDEP in drug-resistant epilepsypatients treated with VNS therapy
Ryvlin P, So EL, Gordon CM, Hesdorffer DC, Sperling MR, Devinsky O, Bunker MT, Olin B, Friedman D.
Epilepsia. 2018 Mar;59(3):562-572.